FDA clarifies policies for compounders as national GLP-1 supply …
The U.S. Food and Drug Administration has determined the shortage of tirzepatide injection, a glucagon-like peptide 1 (GLP-1) medication, has been resolved. Tirzepatide injection has been in...
'Staggeringly high' discontinuation rates for GLP-1 drugs like …
1 day ago · Credit: Markus Winkler from Pexels. The use of diabetes and weight-loss medications like Ozempic or Wegovy—called GLP-1 drugs—has exploded in recent years, with 12% of U.S. adults having used ...
Glucagon-like peptide-1 receptor: mechanisms and advances in …
Sep 18, 2024 · The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital component of the G protein-coupled receptor (GPCR) family and is found primarily on the surfaces of various cell...
Special Report: Potential Strategies for Addressing GLP-1 and Dual …
Apr 7, 2023 · Unexpected drug shortages of the long-acting glucagon-like peptide 1 (GLP-1) receptor agonists dulaglutide and semaglutide and the dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist tirzepatide emerged in late 2022 and have persisted through the first quarter of 2023 (1).
Research shows GLP-1 drugs are effective but complex - UChicago …
May 30, 2024 · While experts caution against overusing GLP-1RAs or viewing them as a universal cure-all for obesity, physicians and researchers agree that the drugs are highly effective for weight management and Type 2 diabetes treatment.
Science’s Breakthrough of the Year: GLP-1 agonists can blunt …
Dec 15, 2023 · Science has named the development of glucagon like peptide-1 (GLP-1) agonists and this year's discovery that these drugs can blunt obesity-associated health problems as its 2023...
From diabetes drug to anti-inflammation powerhouse: The …
Dec 18, 2023 · Known as GLP-1 receptor agonists, for glucagon like peptide 1, these medications mimic the gut hormone GLP1, which regulates blood sugar levels and appetite. Among them are the popular weight...
Glucagon-like peptide-1 receptor agonists before upper ... - The …
Oct 22, 2024 · Objective To assess whether use of glucagon-like peptide-1 (GLP-1) receptor agonists before upper gastrointestinal endoscopy is associated with increased risk of pulmonary aspiration or discontinuation of the procedure compared with sodium-glucose cotransporter-2 (SGLT-2) inhibitors. Design Cohort study. Setting Two deidentified US commercial healthcare databases. Participants 43 365 adults ...
Discontinuation of Glucagon-Like Peptide-1 Receptor Agonists
Nov 13, 2024 · This Viewpoint summarizes the clinical, policy, and equity implications of GLP-1 RA discontinuation and proposes solutions for a path forward. Clinical Implications of GLP-1 RA Discontinuation. Discontinuing GLP-1 RA therapy has important clinical implications. In the STEP-1 extension 3 and STEP-4 trials, 4 two-thirds of the weight lost on ...
Glucagon-like peptide-1 receptor agonists: What to know
Jun 22, 2020 · Glucagon-like peptide-1 receptor agonists (GLP-1 agonists) are one option. In this article, Dr. Maria Prelipcean explains how GLP-1 agonists work, their benefits and risks, and some common...