In the three years since Christina Applegate was diagnosed with multiple sclerosis, the actress’ medical condition has steadily progressed. During a recent episode of her podcast MeSsy — co-hosted with Jamie-Lynn Sigler, who also received a MS diagnosis — she detailed the chronic pain she faces and how it impacts her daily life.

I lay in bed screaming'Christina Applegate has shared the grueling effects of her battle with Multiple Sclerosis. The “Dead To Me”