INDIANAPOLIS — The northbound lanes of Interstate 65 in downtown Indianapolis are closed after a fiery crash involving a semi ...

The Rhesus macaque primates escaped from the Alpha Genesis facility Wednesday when a new employee didn't fully shut an ...

The pope – or someone in the Vatican communications office – has been inadvertently rooting for the Saints even as they lost ...

"America's Got Talent" champion Richard Goodall sang the national anthem before Indiana State's men's basketball game against ...

Seeing their options narrow, Democrats focused on flipping a handful of seats in Arizona, California and Oregon to close the ...

More than 50 volunteers with the Home Depot Foundation remodeled two homes for veterans in Indianapolis. INDIANAPOLIS — In ...

INDIANAPOLIS — Our Dave Calabro is on the hunt for positive and uplifting stories, and this week he's at the 75th annual ...

Trey Mock created the Colts' beloved mascot in 2006 and has spent 19 seasons entertaining fans and connecting with members of ...

INDIANAPOLIS — The 17th annual CNO Financial Indianapolis Monumental Marathon is Saturday in downtown Indianapolis. It's among the 15 largest races in the country. Thousands are ready to take off from ...

Midway through his first season in Indy, Joe Flacco has taken hold of the starting job and is now trying to figure out how to ...

A woman from Carmel brought this sign to hold outside the Carroll County Courthouse during the Delphi murders trial. The jury ...

Trump campaigned on giving police officers immunity from prosecution, although he also said such immunity might “depend” on ...