“We knew that it was important to focus on the integrin family of proteins,” says Shiokawa. “Our hypothesis was that the autoantigen of autoimmune pancreatitis is related to the autoantigen ...

The detailed sequence of events following ECM binding to the integrin is not known ... Upon activation, FAK combines with Src or Fyn — Src-family kinases — which then phosphorylate paxillin ...

Background Beta-2 integrin (CD18) and the Src-family kinases (Hck, Fgr, Lyn) are required for development of autoimmune arthritis in vivo. Immune cell or platelet derived extracellular vesicles (EV) ...

The Integrin Alpha 4 pipeline drugs market research report outlays comprehensive information on the Integrin Alpha 4 targeted therapeutics, complete with analysis by indications, stage of development, ...