Advanced model predicts gene architecture via nucleosome position
DNA—the molecule that carries the genetic information of all living organisms—is packaged within cells in a complex manner ...
EurekAlert!10d
Structure of a eukaryotic CRISPR-Cas homolog, Fanzor2, shows its promise for gene editing
Scientists at St. Jude Children’s Research Hospital revealed how Fanzor2’s divergence from bacterial ancestors may make it a ...
eLife2d
Negative cell cycle regulation by calcineurin is necessary for proper beta cell regeneration in zebrafish
Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.
Structure of a eukaryotic CRISPR-Cas homolog, Fanzor2, shows promise for gene editing
Scientists at St. Jude Children's Research Hospital have revealed how Fanzor2's divergence from bacterial ancestors may make ...
EurekAlert!10d
Structure of a eukaryotic CRISPR-Cas homolog, Fanzor2, shows its promise for gene editing (IMAGE)
Elizabeth Kellogg, PhD, St. Jude Department of Structural Biology, used cryo-EM to study the evolutionary journey of Fanzor2, a compact eukaryotic genome-editing protein with huge potential.