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WEB3 days ago · Gut is a Plan S compliant Transformative Journal.. Gut is a leading international journal in gastroenterology and hepatology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas.Gut delivers up-to-date, authoritative, clinically oriented coverage in all areas of gastroenterology and hepatology.
Gut microbiome and health: mechanistic insights | Gut
WEBThe gut microbiota is now considered as one of the key elements contributing to the regulation of host health. Virtually all our body sites are colonised by microbes suggesting different types of crosstalk with our organs. Because of the development of molecular tools and techniques (ie, metagenomic, metabolomic, lipidomic, metatranscriptomic), the complex interactions occurring between the ...
The road to a world-unified approach to the management of ... - Gut
WEBObjective During the last decade, the management of gastric intestinal metaplasia (GIM) has been addressed by several distinct international evidence-based guidelines. In this review, we aimed to synthesise these guidelines and provide clinicians with a global perspective of the current recommendations for managing patients with GIM, as well as highlight evidence gaps that need to be addressed ...
The gut microbiota and host health: a new clinical frontier
WEBBox 2 Potential therapies aimed at modulation of the gut microbiota. Probiotics: Live microorganisms that, when administered in adequate amounts, confer a health benefit on the host.107, 108 Examples include strains of the genera Bifidobacterium and Lactobacillus.Probiotics can have multiple interactions with the host,109 including competitive inhibition of other microbes, effects on mucosal ...
Multiomics of the intestine-liver-adipose axis in multiple studies ...
WEB2 days ago · Background The microbiota is emerging as a key factor in the predisposition to insulin resistance and obesity. Objective To understand the interplay among gut microbiota and insulin sensitivity in multiple tissues. Design Integrative multiomics and multitissue approach across six studies, combining euglycaemic clamp measurements (used in four of the six studies) with other measurements of ...
Human gut microbiome: hopes, threats and promises | Gut
WEBThe microbiome has received increasing attention over the last 15 years. Although gut microbes have been explored for several decades, investigations of the role of microorganisms that reside in the human gut has attracted much attention beyond classical infectious diseases. For example, numerous studies have reported changes in the gut microbiota during not only obesity, diabetes, and liver ...
Stomach microbiota in gastric cancer development and clinical
WEBJun 17, 2024 · Gastric cancer (GC) is one of the most common malignancies and a prominent cause of cancer mortality worldwide. A distinctive characteristic of GC is its intimate association with commensal microbial community. Although Helicobacter pylori is widely recognised as an inciting factor of the onset of gastric carcinogenesis, increasing evidence has indicated the substantial involvement of microbes ...
Gut microbiota composition reflects disease severity and …
WEBObjective Although COVID-19 is primarily a respiratory illness, there is mounting evidence suggesting that the GI tract is involved in this disease. We investigated whether the gut microbiome is linked to disease severity in patients with COVID-19, and whether perturbations in microbiome composition, if any, resolve with clearance of the SARS-CoV-2 virus. Methods In this two-hospital cohort ...
Gut microbiome stability and resilience: elucidating the response …
WEBThe human gut microbiome is a complex ecosystem, densely colonised by thousands of microbial species. It varies among individuals and depends on host genotype and environmental factors, such as diet and antibiotics. In this review, we focus on stability and resilience as essential ecological characteristics of the gut microbiome and its relevance for human health. Microbial diversity ...
Dynamics of the gut microbiome in FAP patients undergoing …
WEBAug 1, 2024 · In their review, Inamura et al. 1 emphasise the need for prospective cohort studies to establish the role of the microbiome as an essential exposome in tumourigenesis. However, establishing the relationship between gut microbiota and sporadic colorectal cancer (CRC) is challenging due to the extended time required for precancerous lesions to develop into cancer.2 Thus, we believe the rapid ...